| Bioactivity | [Glp5,(Me)Phe8,Sar9] Substance P (5-11) (DiMe-C7) is a Substance P (HY-P0201) analogue that has approximately the same effects as Substance P (HY-P0201) on neurokinin 1 receptor (NK1R) in rat brain, but with a much longer duration of action. [Glp5,(Me)Phe8,Sar9] Substance P (5-11) selectively activates dopamine metabolism in the mesencephalon and midbrain cortex of the rat brain. [Glp5,(Me)Phe8,Sar9] Substance P (5-11) also increases motor activity and induces recovery of cocaine-seeking behavior in rats[1][2][3]. |
| Name | [Glp5,(Me)Phe8,Sar9] Substance P (5-11) |
| CAS | 77128-69-9 |
| Sequence | pGlu-Gln-Phe-N-Methyl-Phe-Sar-Leu-Met-NH2 |
| Shortening | pGlp-QF(-Me)F-Sar-LM-NH2 |
| Formula | C43H61N9O9S |
| Molar Mass | 880.06 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |